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Research


Outpatient Stroke Research


The Mercy Stroke Center is participating in the following outpatient stroke research trials:

TRIAL NAME:
PRoFESS - Prevention regimen for avoiding second strokes

Description:
This is a long-term prevention study looking at several approved medications for the prevention of stroke.
The study is predicted to last four years.

Patient Must:

  • Have had a stroke within the last three months
  • Be able to take medications by mouth
  • Be able to participate for four years of follow-up visits
  • Be 55 years or older

Patients Must Not:

  • Need to take an anticoagulant such as warfarin
  • Be pregnant or breast feeding

Contact: Susan Croopnick, RN at (916) 733-6829, or e-mail scroopnick@chw.edu

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TRIAL NAME:
SWISS - Siblings With Ischemic Stroke Study 

Description:
NIH-sponsored study looking at genetic markers for stroke.

Patients Must:

  • Have had a stroke in the past six months
  • Have a living brother or sister who has had a stroke
  • Be between 18-80 years of age

Patients Must Not:

  • Have had a stroke within two days after a heart or brain procedure or two months following trauma

Contact: Deidre Wentworth, RN at (916) 453-4233, or e-mail dwentworth@chw.edu

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TRIAL NAME:
COSS - Carotid Artery Occlusion Surgery Study

Description:
NIH study investigating surgical bypass in patients with a blocked carotid artery compared to standard medical
treatment. This study will use PET scan technology to determine eligibility.

Patients Must:

  • Have evidence of a 100% occlusion of one carotid artery
  • Have had a stroke or TIA within the last three months
  • Be willing to participate for two years of follow-up visits
  • Be over the age of 18

Patients Must Not:

  • Have a blockage greater than 50% of the other carotid artery
  • Be pregnant or breast feeding

Contact: Deidre Wentworth, RN at (916) 453-4233, or e-mail dwentworth@chw.edu

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TRIAL NAME:
CLOSURE I - Patent foramen ovale in stroke study

Description:
A study investigating the use of a device to treat a heart defect that consists of a hole between the heart chambers.
This defect is called a "patent foramen ovale." The study compares this device to standard medical treatment
in patients who have had a stroke due to this condition.

Patients Must:

  • Have evidence of a patent foramen ovale demonstrated by echocardiogram
  • Have had a stroke or TIA in the past six months
  • Be willing to participate in study for two years of follow-up visits
  • Be between 18-50 years of age

Patients Must Not:

  • Require anticoagulation medication such as warfarin for another condition
  • Be pregnant or breastfeeding
  • Have heart valve disease

Contact: Susan Croopnick, RN by phone at (916) 733-6829, or e-mail scroopnick@chw.edu

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